Prognostic significance of TERT promoter and BRAF mutations in TIR-4 and TIR-5 thyroid cytology
نویسندگان
چکیده
منابع مشابه
BRAF V600E and TERT Promoter Mutations in Papillary Thyroid Carcinoma in Chinese Patients
BACKGROUND The BRAF V600E and telomerase reverse transcriptase (TERT) promoter mutations have been reported in papillary thyroid carcinoma (PTC). The aim of this retrospective cross-sectional study was to add further information regarding the prevalence of the BRAF V600E and TERT promoter mutations in Chinese PTC and their clinicopathological associations. METHODS We detected the BRAF V600E m...
متن کاملUltrasound and clinicopathological features of papillary thyroid carcinomas with BRAF and TERT promoter mutations
This study is to investigate if any relationship exists between the telomerase reverse transcriptase (TERT) promoter or proto-oncogene BRAF mutation and ultrasound (US) and clinicopathological features of papillary thyroid carcinomas (PTCs). The study included 150 patients with surgically confirmed PTC from October 1994 to December 2004. According to the existence of TERT promoter or BRAF mutat...
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Two mutations (C228T and C250T) in the promoter region of the telomerase reverse transcriptase (TERT) have recently been described in different types of cancer including follicular cell-derived thyroid cancer (TC). In this paper, we reviewed the rates of these mutations in different types and subtypes of TC, their association with a number of clinical and histopathological features and outcome ...
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Papillary thyroid carcinoma (PTC) is the most common type of endocrine malignancy and accounts for ~80% of thyroid carcinomas in adults and 90% in children. Risk stratification is important for identifying patients at higher risk and, for this reason, recent advances in molecular genetics of thyroid cancer can be applied to provide novel biomarkers useful in understanding tumor behavior. B-Raf ...
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ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 2019
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje-19-0073